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Human-derived content of dust microbiota in athletic facilities reflects building design and operation

Ryan Blaustein, et al.
Civil and Environmental Engineering
Building design and operation impact the accumulation and survival of microorganisms in indoor spaces. These microorganisms, together referred to as the indoor microbiome, have implications for human health and well being. However, the relative importance of factors like architecture compared to, e.g., human occupancy, remains unclear. This study aimed to... View the poster.

Comparison of transmission dynamics in different networks

Hyojun Lee, et al.
Chemical and Biological Engineering
Contagion processes arise broadly in the social and biological sciences, manifested as, for example the spread of infectious and the diffusion of innovations. Depending on the network structure, the transmission dynamics can have different. However, when the structure is too complex (e.g. multipartite networks), understanding the properties of the network... View the poster.

Creating a Framework for Evaluating the Effectiveness of Various Search Strategies in the Small-World Phenomenon

Matt Nicholson, et al.
Electrical Engineering and Computer Science
Milgram’s small-world experiments provided evidence for six degrees of separation, only a chain of five contacts separates any two random people. In theory, this small-world phenomenon is prevalent from a network structure perspective. However, empirical evidence shows that successful message chains are occasional, and the length of message chains are... View the poster.

Insights into antibiotic-resistance gene dissemination in dust microbiomes

Sarah Ben Maamar, et al.
Civil and Environmental Engineering
The advent of next-generation sequencing has made it increasingly feasible to survey microbes in situ, including inside buildings where many people spend extended periods of time. Microbes in buildings, and specifically in dust, are linked to various health outcomes, and the amount of antimicrobial chemicals in dust is associated to... View the poster.

Network Acuity: Social Perceptions in a Small-World Experiment

Sidhartha Jha, et al.
Industrial Engineering and Management Sciences
It is well documented that an individual’s ability to know who knows whom in their network has positive benefits in various facets of professional life. But people vary in their network acuity - that is, their ability to accurately assess who knows whom in their network. This poster seeks to... View the poster.

Programming Prescriptions: A Clinician Usable Patient-Oriented Prescription Programming Language

Spencer P. Florence, et al.
Electrical Engineering and Computer Science
A medical prescription is a set of health care instructions that govern the plan of care for an individual patient; it includes orders for drug therapy, diet, clinical assessment, laboratory testing, and more. Clinicians have long used algorithmic thinking to describe and implement these prescriptions but without the benefit of... View the poster.

SH-ToF: Micro Resolution Time-of-flight Imaging with Super-heterodyne Interferometry

Fengqiang Li, et al.
Electrical Engineering and Computer Science
Three-dimensional imaging techniques have been widely used in both industry and academia. Time-of-flight (ToF) sensors offer a promising method of 3D imaging due to compact size and slow complexity. However, state-of-the-art ToF sensors only have depth resolutions of centimeters due to limitations in the modulation frequencies that can be used.... View the poster.

Life Sciences

Identification of Sources of Platform Specific Bias in Single Cell RNA Sequencing

Rohan Verma, et al.
Pulmonary and Critical Care
High throughput single cell transcriptomics is a powerful tool for unbiased marker-free discovery of the new cell types and activation states. This process involves reverse transcribing RNA using beads containing oligonucleotide bar codes to perform whole genome amplification such that a barcoded cDNA library is produced. This library can then... View the poster.

Quantitative trait meta-analysis identifies rare noncoding variants associated with altered hormone levels in PCOS

Matthew Dapas, et al.
Polycystic ovary syndrome (PCOS) is a complex genetic disorder characterized by hyperandrogenism, chronic anovulation, and polycystic ovarian morphology. PCOS affects up to 15% of premenopausal women worldwide, is the leading cause of anovulatory infertility, and is a major risk factor for type 2 diabetes. A number of susceptibility loci have... View the poster.

Comprehensive analysis of transcriptional response upon multiple drug treatments

Yizhen Zhong, et al.
Investigating the drug response at the transcriptional level is powerful for understanding the mechanism of drug adverse effects, elucidating inter-individual drug response variability and developing personalized therapies. However, drug perturbation experiments are limited to immortal cell lines which do not reflect the true physiology and gene expression of the liver,... View the poster.

Computational tool for multimodal brain imaging

Runfeng Tian, et al.
Physical Therapy and Human Movement Sciences
After stroke, motor recovery usually occurs with functional changes in the sensorimotor network rather than healing damaged brain areas. Clinical assessments and structural brain imaging techniques (CT/MRI) provide an overview of stroke severity and anatomical damages but cannot reveal the dynamic changes of brain function. Electroencephalography (EEG) as a non-invasive... View the poster.

Lost in translation: Mutating the ribosome active site in vitro

Anne d'Aquino, et al.
Interdisciplinary Program in Biological Sciences
The ribosome, a 2.5-MDa molecular machine that polymerizes α-amino acids into proteins, is the catalytic workhorse of the translation apparatus. The catalytic capacity of the translation machinery has attracted extensive efforts to repurpose it for novel functions. One key idea is that the natural translation machinery can be harnessed to... View the poster.

mutSignatures: An R Package For Extraction And Analysis Of Cancer Mutational Signatures

Damiano Fantini, et al.
Genetic instability is one of the hallmarks of cancer. Neoplastic cells accumulate somatic mutations in their genomes, resulting in aberrant homeostasis, cancer cell survival, and proliferation. Different genetic instability processes result in distinct non-random patterns of DNA mutations, also known as mutational signatures. The interest in the identification of mutational... View the poster.

Physical Sciences

How Black Holes Shape Globular Clusters

Shi Ye, et al.
Physics and Astronomy
Numerical simulations have shown that black holes (BHs) have significant influence on the evolution of globular clusters (GCs), and therefore shape their observational features. Recently, a BH-main sequence star (MS) binary system has been observed in the Milky Way GC NGC 3201. Our group uses Cluster Monte Carlo (CMC) code... View the poster.

Multi-Index Attribution of Beijing's 2013 Airpocalypse

Christopher W. Callahan, et al.
Environmental Sciences
Poor air quality causes 2 to 4 million premature deaths per year globally. Individual high-impact events, like Beijing’s January 2013 “airpocalypse,” have drawn significant attention, as they have demonstrated that short-lived air quality events can have outsized effects on public health and economic vitality. Poor air quality events are the... View the poster.

Simulating 3-D Biosignature Gases on Earths around other Stars

Howard Chen, et al.
Earth and Planetary Sciences
The search for life beyond Earth is one of the big questions in the modern science community, and a primary motivation behind a range of NASA's ground-based and space-bourne missions. In the near future, the James Webb Space Telescope, LUVOIR, and HabEx will characterize the atmospheres of nearby Earth-like exoplanets.... View the poster.

Drivers of Seasonal Variability of Atmospheric Stagnation Features Under Anthropogenic Forcing Using a Climate Model Ensemble (CMIP5)

Yuxi Suo, et al.
Earth and Planetary Sciences
Air pollution increases mortality risk up to 18 percent due to cardiovascular causes. Poor air quality occurs more when meteorological components prevent the dispersal of pollutants in the lower atmosphere. The atmospheric and hydrological patterns change as global warming alters the pattern of circulations seasonally. The purpose of this study... View the poster.

Is Classifying Secondary Seismic Signals Scalable and Automatable?

Vivian Tang, et al.
Earth and Planetary Science
Seismic waves from large-magnitude earthquakes sometime trigger small secondary earthquakes or tectonic tremor. These secondary signals are important to observe and study because their occurrence reflects on the state of stress of the subsurface, which is important for hazard assessment. Here we first report on how individual inspection by a... View the poster.

Prediction of Black Hole Populations in Globular Clusters

Newlin Weatherford, et al.
Physics and Astronomy
Recent discoveries of black hole (BH) candidates in galactic and extragalactic globular clusters (GCs) have ignited interest in understanding how BHs dynamically evolve in a GC and the number of BHs (NBH) that may still be retained by today's GCs. Numerical models show that even if stellar-mass BHs are retained... View the poster.

Probing Massive Black Hole Populations and Their Environments with LISA

Michael Katz, et al.
Physics and Astronomy
ESA and NASA are moving forward with plans to launch LISA around 2030. With data from the Illustris large-scale cosmological simulation, we provide analysis of LISA detection rates accompanied by characterization of the merging massive black holes and their host galaxies. Massive black holes of total mass are the main... View the poster.

Social Sciences

Strategic failure? The impact of failed legislation on enacted legislation

Amanda Jadidi d'Urso
Political Science
In an environment with limited time and resources, why do some legislators repeatedly sponsoring the same bills that never pass? Are they only appealing to constituents or lobbyists, or do they reintroduce legislation for strategic purposes? Bachrach and Baratz (1962) characterize the second-face of power as having control over agenda-setting.... View the poster.